Chicken Marsala Casserole is a comforting and flavorful twist on the classic Italian-American dish, Chicken Marsala. Traditionally, Chicken Marsala features pan-seared chicken cutlets simmered in a rich sauce made from Marsala wine, mushrooms, and herbs.
This casserole version takes those beloved flavors and transforms them into a hearty, baked meal that’s perfect for family dinners, potlucks, or make-ahead meal prep. Juicy chunks of chicken are combined with tender pasta, earthy mushrooms, creamy sauce, and melted cheese, then baked until bubbly and golden.
Chicken Marsala Casserole transforms the rich, restaurant-quality flavors of the classic Italian dish into a cozy, baked, family-style meal. With tender chicken, mushrooms, and a creamy Marsala wine sauce, this casserole offers all the elegance of traditional Chicken Marsala in a fuss-free, comforting format.
It’s perfect for dinner parties, family meals, or meal prep — rich, savory, and deeply satisfying, with minimal effort and major flavor. Plus, it’s easy to customize with pasta, rice, or veggies!
The Marsala wine lends a slightly sweet, nutty flavor that pairs beautifully with the savory elements, while the baking process allows all the flavors to meld together in a satisfying way.
It’s a dish that feels both elegant and homey—ideal for a cozy weeknight meal yet impressive enough for guests. The casserole format also makes it easy to prepare in advance and simply pop in the oven when needed, saving you time without sacrificing taste.
Whether you’re a fan of the original Chicken Marsala or just looking for a comforting, crowd-pleasing casserole, this recipe delivers a warm, indulgent experience that will quickly become a household favorite.
This Chicken Marsala Casserole is creamy, savory, and packed with mushrooms and chicken in a rich Marsala sauce, then baked to bubbly perfection.
It’s a warm and comforting one-dish dinner that delivers restaurant-level flavor at home.
In a skillet, heat olive oil and butter over medium heat.
Add onions, garlic, and mushrooms. Sauté until softened and browned, about 6–8 minutes.
Pour in Marsala wine and cook 2–3 minutes.
Add chicken broth, cream, thyme, Italian seasoning, salt, and pepper.
Simmer for 5 minutes until slightly thickened.
In a greased 9x13 baking dish, layer the cooked chicken (and pasta or rice, if using).
Pour sauce over chicken. Top with Parmesan and mozzarella.
Cover with foil and bake at 375°F for 25 minutes.
Remove foil and bake 10 more minutes until golden and bubbly.
Garnish with fresh parsley and serve warm with crusty bread or salad.
Servings 6
* Percent Daily Values are based on a 2,000 calorie diet. Your daily value may be higher or lower depending on your calorie needs.
Refrigeration: Allow the casserole to cool completely before storing. Transfer to an airtight container or cover the baking dish tightly with foil or plastic wrap. It will keep well in the refrigerator for up to 3–4 days. Reheat individual portions in the microwave or the whole casserole in a 350°F (175°C) oven until heated through, covering with foil to prevent drying.
Freezing: For longer storage, prepare the casserole up to the point of baking. Wrap tightly in a double layer of plastic wrap and foil, or store in a freezer-safe container. Freeze for up to 3 months. Thaw overnight in the refrigerator before baking as directed, adding 5–10 minutes to the baking time.
Meal Prep Tip: Portion the casserole into individual, freezer-safe containers for easy grab-and-reheat lunches or dinners.
Avoid Overheating: Overcooking during reheating can cause the chicken to become dry. To keep it moist, add a splash of chicken broth or cream before reheating.
In conclusion, Chicken Marsala Casserole brings the rich, savory flavors of a classic Italian dish into a convenient, comforting casserole format. This dish takes tender chicken, earthy mushrooms, and the signature Marsala wine sauce and combines them in a way that’s both hearty and satisfying.
The creamy sauce, made from a blend of Marsala wine, chicken broth, and a touch of cream, envelops the chicken and mushrooms, while the casserole itself bakes to perfection, creating a deliciously golden, bubbling top layer.
What makes this casserole truly stand out is its ability to marry the bold flavors of Chicken Marsala with the ease of a one-pan meal. The chicken remains juicy, while the mushrooms absorb all the rich, aromatic flavors of the sauce, creating a depth of taste that’s deeply satisfying.
With the addition of cheese and breadcrumbs on top, this casserole achieves the perfect balance of creamy, crispy, and savory in every bite.
This recipe is incredibly versatile, allowing you to adjust ingredients based on your preferences. You can use boneless, skinless chicken breasts or thighs for added richness, and feel free to substitute the mushrooms with other vegetables, such as onions or spinach.
The casserole can also be made ahead and refrigerated or frozen, making it a fantastic choice for meal prep or busy weeknights.
Whether you’re serving it for a family dinner, a cozy gathering, or a special occasion, Chicken Marsala Casserole provides all the warmth and flavor of a traditional Chicken Marsala, with the convenience of a casserole.
The comforting, creamy sauce, tender chicken, and savory mushrooms combine to create a dish that feels elegant yet simple, making it a dish you’ll want to return to time and again.
